Benz[a]azulenequinones: Reaction of Benz[a]azulenes with Pyridinium Hydrobromide Perbromide

Synthesis and Analgesic activity of certain 2-Oxazolines

Oxazoline is one of the 5 membered heterocycle ring can be synthesized in many ways and various activities like analgesic, antimicrobial and antidiabetic activity are well documented. In the present study analgesic activity screened by tail flick and tail immersion model.The synthesized compounds are ideally characterized spectrophotometrically. Chlorinated and methoxylated oxazolines found to ...

One-Pot Synthesis of Some New α-Bromoketals and Acetals via 1,8-Diazabicyclo[5.4.0] Undec-7-ene-Hydrobromide-Perbromide

α-Bromoketals and acetals are important synthetic precursors in organic synthesis. In this work, some new α-bromoketals are synthesized by the reaction of aryl methyl ketones with diols in the presence of 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) hydrobromide-perbromide in good isolated yields. The latter compound converts aldehydes to acetals and serves as a new and efficient reagent for t...

Electrophilic Aromatic Substitution of Catechins: Bromination and Benzylation

Relative yields of C-6, C-8. and C-6 and C-8 substituted catechins obtained from the reaction of (+ )-catechin or 3' 4',57-tetra-O-methvl-( + )-catechin with pyridinium hydrobromide-perbromide, bromine. p-hydroxybenzyl al~oh~I, or o-hydroxybenZyI alcohol showed differing selectivities depending upon the electrophile used. Ratios of C-6 to C-8 substituted products were 1 : 1.2 for the reaction o...

Pyridinium Salts, Insertion Reaction, Oximes Pyridinium Salts with electron-withdrawing groups in the 3-position react with aliphatic ketoximes

Die Anlagerung von Nucleophilen an quartäre Pyridinium-Salze ist seit langem bekannt [2], ebenso die Beobachtung, daß Ringöffnungsund Umlagerungsreakt ionen sich anschließen können, gerade bei der Einwirkung von z.B. Hydroxidoder Alkoxid-Ionen und Aminen [3, 4]. Quartäre Salze von Pyridincarbaldoximen, die ausgeprägt hydrophile Eigenschaf ten haben, werden als Reaktivatoren bei In toxika t ion ...

Polymorphic Study of (-)-galanthamine Hydrobromide